Oriented cell growth on self-assembled bacteriophage M13 thin films.
نویسندگان
چکیده
Fibrillar M13 bacteriophages were used as basic building blocks to generate thin films with aligned nanogrooves, which, upon chemical grafting with RGD peptides, guide cell alignment and orient the cell outgrowth along defined directions.
منابع مشابه
Self-assembled monolayers induced inter-conversion of crystal structure by vertical to lateral growth of aluminium doped zinc oxide thin films.
In this communication, we demonstrate the inter-conversion of crystal structure of aluminium doped zinc oxide (AZO) thin films from highly (002) plane oriented vertical growth to (103) plane oriented lateral growth by adjusting the polarity of the self-assembled monolayers (SAMs) on glass substrates at room temperature.
متن کاملImplementing chemical functionality into oriented films of metal–organic frameworks on self-assembled monolayers
The generation of thin films of oriented functionalized metal–organic frameworks (MOFs) on self-assembled monolayers was achieved via direct growth from solution. Specifically, the direct growth from solvothermally pretreated synthesis solutions of two different MOF structures with amino functionality was investigated: the flexible framework structure NH2–Fe–MIL-88B and the mesoporous MOF NH2–F...
متن کاملCell-specific targeting by engineered M13 bacteriophage expressing VEGFR2 nanobody
Objective(s): Filamentous bacteriophage M13 was genetically engineered to specifically target mammalian cells for gene delivery purpose. Materials and Methods: A vascular endothelial growth factor receptor 2 (VEGFR2)-specific nanobody was genetically fused to the capsid gene III of M13 bacteriophage (pHEN4/3VGR19). A mammalian expression construct containing Cop-green fluorescent protein (Cop-G...
متن کاملProbing the Self-Organization Kinetics in Block Copolymer Films
Solvent annealing [1-3] has recently emerged as a powerful alternative to thermal annealing of block copolymer (BCP) thin films and nanocomposites. Taking a more general point of view, solvent treatment procedures, employing the selectivity of the solvents towards the different blocks, can produce new structures [4], and provide fascinating insights into the swelling kinetics and instabilities ...
متن کاملHighly oriented surface-growth and covalent dye labeling of mesoporous metal-organic frameworks.
Mesoporous amino-functionalized metal-organic framework thin films with the UiO-68 topology were grown in a highly oriented fashion on two different self-assembled monolayers on gold. The oriented MOF films were covalently modified with the fluorescent dye Rhodamine B inside the pore system, as demonstrated with size-selective fluorescence quenching studies. Our study suggests that mesoporous m...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Chemical communications
دوره 41 شماره
صفحات -
تاریخ انتشار 2008